Gov. Blagojevich, Comptroller Hynes
announce $10 million in state stem cell research grants
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Ten grants awarded to Illinois
hospitals and universities to conduct critical stem cell research
[APRIL 25, 2006]
CHICAGO -- On April 24, Gov. Rod R. Blagojevich
and Comptroller Dan Hynes announced 10 grants worth a total of $10
million for the lifesaving work of stem cell research at several
Illinois hospitals and research institutions. Last summer, by
executive order, Blagojevich and Hynes created the Illinois
Regenerative Medicine Institute, making Illinois the first state in
the Midwest, and only the fourth state in the nation, to commit
public funds to stem cell research. Researching and studying stem
cells allows scientists and doctors to better understand what causes
serious medical illnesses and conditions such as Alzheimer's,
diabetes, spinal cord injury, stroke and heart disease, in hopes of
discovering new ways to treat or even cure them.
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"This is the first time Illinois
is awarding state-funded grants for stem cell research, and that
makes today an important day for our state," Blagojevich said. "The
promise of stem cell research is unlimited. We need to do everything
we can to help our scientists and researchers make the most of it."
"In the world of medical research, the fight for cures is waged
one grant at a time," said Hynes. "Today, I am proud to say we've
given our scientists 10 million more weapons to win that fight. In
so doing, we are also giving hope to the millions of Americans who
suffer from debilitating diseases that stem cell research has the
potential to defeat."
"Today's investments in stem cell research are vital to finding
cures for life-threatening diseases that afflict thousands of
Illinois citizens," said Lt. Gov. Pat Quinn, who has also been a
steadfast supporter of stem cell research in the state.
"Today marks an important step not only for the medical research
community in Illinois, but also for the many people who hope to one
day benefit from the cures and treatments their research will help
develop," said Rep. Sara Feigenholtz, D-Chicago. "I am pleased to
stand with Governor Blagojevich and Comptroller Hynes in affirming
the state's commitment to this potentially lifesaving research."
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The governor's executive order last July directed the Illinois
Department of Public Health to create a program to award $10 million
in grants for stem cell research. The department developed the
Illinois Regenerative Medicine Institute after looking at stem cell
research efforts already under way in Illinois and determined the
best method of awarding the grant money to yield the greatest
benefits. The department also created a panel, consisting of two
bioethicists and six medical professionals with expertise in stem
cells, to review grant applications. The panel members are from
Ireland and all over the United States, with the exception of
Illinois.
"We received 24 applications for stem cell research grants, all
of which were innovative and had great potential," said Illinois
Department of Public Health Director Dr. Eric E. Whitaker. "With the
grants awarded today, we are looking forward to the groundbreaking
medical advancements for many debilitating diseases that stem cell
research will yield."
Grants were awarded to the following institutions:
-
$870,000 --
Guillermo A. Ameer, Northwestern University, for stem-cell-based
vascular tissue engineering to enable the development of
replacement blood vessels and therefore eliminate the need to
harvest existing blood vessels from the patient.
-
$800,000 -- George
H. DeVries, University of Illinois at Chicago, for stem cell
therapy for recovery from ischemic stroke.
-
$1,999,944 -- Mary
J. Hendrix, Children's Memorial Hospital, for reversal of
disease progression by stem cells.
-
$1,990,309 --
Ronald Hoffman, University of Illinois at Chicago, for the
Center for the Development of Stem Cell Therapies for Human
Diseases to focus on the use of human embryonic stems cells and
adult tissue-specific stem cells for the treatment of blood
disorders, lung diseases and heart repair.
-
$800,000 --
Gwendolyn L. Kartje, Hines VA Hospital, for human adult
bone-marrow-derived stem cell therapy for recovery from ischemic
stroke.
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$250,000 -- Stephen
J. Kaufman, University of Illinois at Urbana-Champaign, for
therapeutic implementation of mesoangioblast stem cells in
muscular dystrophy to advance stem cell therapy for muscle and
neurodegenerative disease and injury and provide a mechanism for
repairing a variety of diseased tissues.
-
$473,212 -- Dorothy
A. Sipkins, University of Chicago, for mechanisms of
hematopietic stem cell homing in normal and disease states, with
the goal of understanding the molecular signals that
blood-producing cells use to travel to specific areas where
these cells can survive and regenerate.
-
$1,400,000 --
Patrick J. Stiff, Loyola University, for unlocking the clinical
potential of stem cells derived from umbilical cord blood for
use as blood cells as well as other tissues, including the heart
muscle and nerves.
-
$564,512 --
Xiaozhong A. Wang, Northwestern University, for genetic control
of pluripotency and differentiation in embryonic stem cells to
control the self-renewal and multipotency of stem cells.
-
$591,322 -- Matthew B. Wheeler,
University of Illinois at Urbana-Champaign, for mesenchymal stem
cells, using high-speed robot to culture, screen and
differentiate stem cells as well as assess their suitability as
an alternative to bone marrow as a source of adult stem cells in
tissue-engineered devices for the clinical reconstruction of
bone and soft tissue defects, using human patient-derived fat.
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Stem cells are cells that have the potential to develop into many
different types of healthy new cells in the body. As described by
the National Institutes of Health, they act like an internal repair
system for the body. Stem cells can divide to replenish other cells
for as long as the body is alive. When a stem cell divides, each new
cell has the potential to either remain a stem cell or become
another type of cell, like a muscle cell, a red blood cell or a
brain cell.
Studying stem cells allows doctors to analyze how cells transform
into other cells. Many of the most serious illnesses or birth
defects are caused by problems during the transformation process.
Understanding the process better may help doctors discover how to
prevent, treat or cure illnesses and conditions.
A potential way to use stem cells is to make new cells or tissues
for medical therapies. Currently, donated organs and tissues are
used to replace those that are diseased or destroyed. But there are
far more people who need organ transplants than there are organs
available. Some stem cells offer the possibility of making
replacement cells and tissues to treat various diseases and organ
conditions, including Alzheimer's, spinal cord injury, stroke,
burns, heart disease, diabetes, osteoarthritis and rheumatoid
arthritis, before organs need replacement.
The grantees are required to provide the Department of Public
Health with semiannual and annual reports of progress on their
research. Additionally, they will report to their institutional
review board and receive annual approval for continuance from them.
The Illinois Regenerative Medicine Institute program is designed
to issue grants for stem cell research to study therapies,
protocols, medical procedures, possible cures for and potential
mitigations of major diseases, injuries and orphan diseases; to
support all stages of the process of developing cures, from
laboratory research through successful clinical trials; and to
establish the appropriate regulatory standards for research and
facilities development.
[News release from the governor's
office] |