Jamal Crawford had 29 points for the Knicks, who have lost 17 of 19 but stayed competitive into the fourth quarter. The Hornets trailed 95-91 with 10:20 left before putting away the game with a 26-9 run, getting 12 points from Peja Stojakovic during that spurt.
Stojakovic finished with 22 points and David West added 17 for the Hornets, who won their 10th in a row at home. They were coming off a season-high, six-game road trip in which they went 5-1.
New Orleans (53-22), which never has been better than a No. 4 seed in the playoffs, increased its lead on the top of the West to 1 1/2 games over the San Antonio Spurs, who lost to Utah.
New York (20-56) finished an 0-5 road trip. The Knicks played well for 3 1/2 quarters but could not sustain that effort down the stretch as embattled coach Isiah Thomas missed an opportunity to impress new president of basketball operations Donnie Walsh.
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Paul and Stojakovic took over after the Hornets fell behind in the fourth quarter. Paul came up with a steal and an assist to Bonzi Wells for a transition layup to give New Orleans the lead for good, 97-95. Seconds later, Paul had an easy basket after another Knicks turnover.
New York called a timeout and cut the deficit to 99-98, but Stojakovic drained two 3-pointers to give the Hornets a 107-100 lead with 5:56 left. Paul then hit five straight free throws as New Orleans built its advantage to 117-104.
Reserve Nate Robinson scored 23 points for New York and Zach Randolph added 22, 11 in the first quarter. The Knicks lost despite shooting 55 percent. They led 48-40 midway through the second quarter, before Paul scored 13 points in the last 5:15 of the half to put the Hornets ahead 60-56.