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The recipient was not shown a picture of the donor, and in animal experiments, "the recipient never looks like the donor," especially when the injuries are severe, Siemionow said. That is because the underlying bone structure is different from person to person.
The hospital posted a statement from the woman's sibling on its Web site.
"We never thought for a moment that our sister would ever have a chance at a normal life again, after the trauma she endured," it says. "But thanks to the wonderful person that donated her organs to help another living human being, she has another chance to live a normal life. Our family cannot thank you enough."
After about three months waiting for a donor similar to the recipient in age, gender, tissue type and skin tone, Siemionow again asked her patient if she wanted to go through with it. "She said 'I'm ready. I've been waiting for this,'" the surgeon said.
Disfigured patients are stuck at home, "hiding from society" and afraid to go out, the surgeon said.
Many more like her exist, and a military grant to the clinic will let them explore the possibility of operating on soldiers left severely disfigured, Siemionow said.
The clinic is absorbing the roughly $200,000 cost of this first transplant because it is an experiment and part of research. They hope to offer more, but are taking this one case at a time for now, Siemionow said.
The world's first partial face transplant was performed in France in 2005 on a 38-year-old woman who had been mauled by her dog. Isabelle Dinoire received a new nose, chin and lips from a brain-dead donor. Apart from some rejection episodes, she has done well.
Two others have received partial face transplants since then -- a Chinese farmer attacked by a bear and a European man disfigured by a genetic condition.
Leading plastic surgeons praised the operation. It's an example of a medical advance "that gives patients their lives back," Dr. John Canady, president of the American Society of Plastic Surgeons, said in a statement.
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On the Net:
Cleveland Clinic:
http://www.clevelandclinic.org/face/
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