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Bay, who hadn't faced Lackey previously, looked bad in striking out in his first two at-bats in. He also doubled in the eighth.
"I was trying to get used to the game," Bay said. "I had never seen him before."
Lester got the Game 1 assignment after Josh Beckett was pushed back to Game 3 because of an oblique problem. He retired his final seven batters, striking out four, and only one outfielder had a putout during his stint. Lester struck out seven and walked one.
The Angels, who wrapped up the AL West title with 2 1/2 weeks left in the regular season, finished with a franchise-best 100-62 record that was tops in the majors. But they lost for the eighth time in 10 postseason home games since winning the 2002 World Series.
Lackey, who won Game 7 of that World Series, allowed two runs and four hits in 6 2-3 innings with three walks and five strikeouts.
Notes: Ortiz extended his hitting streak in AL division series games to 12 with his ninth-inning single. ... Hall of Famer Rod Carew, who celebrated his 63rd birthday Wednesday, threw out the ceremonial first pitch.
Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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