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Last chance for patients to enroll in clinical study for foot and leg ulcers

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[February 23, 2009]  LIBERTYVILLE -- Americans are living longer, but living longer means our aging population is at greater risk for acquiring disease. For those with high cholesterol, diabetes and high blood pressure, peripheral artery disease is of particular concern.

During the past few months, Nicolas Shammas, M.D., of Midwest Cardiovascular Research Foundation, has recruited patients in the Lincoln area to participate in a new investigational research study that seeks to find a new treatment for peripheral artery disease, one of the more challenging diseases associated with the aging process. The research study is now under way throughout the United States.

Why is this study important? Adults with peripheral artery disease often develop severe ulcers of the feet or legs, a condition called critical limb ischemia. There are no prescription drugs currently available to effectively treat critical limb ischemia and only very limited treatments to delay or prevent amputation.

Peripheral artery disease, or PAD, often described as "poor circulation," is diagnosed when the large arteries of the leg narrow, thereby restricting blood flow. The tissues then become starved of the blood, nutrients and oxygen they need, and in the most advanced form of the condition, skin ulcers begin to develop and the health threat is serious. In advanced stages, peripheral artery disease can lead to amputation and in extreme cases, even death.

While these facts present a grim outlook, there is hope with the research being conducted by Shammas on the disease at the stage of critical limb ischemia with foot or leg ulcers. It is anticipated that the investigational study medication may promote new blood vessel growth and may delay the time to amputation or death.

The research study is currently seeking qualified participants. Individuals must be 50 years of age or older with stable skin ulcers or noninfected gangrene on a foot or leg; must be diagnosed with peripheral arterial disease at the stage of critical limb ischemia; and be unsuitable for bypass or revascularization. Additional criteria also apply.

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If you or someone you know suffers with skin ulcers due to peripheral artery disease at the stage of critical limb ischemia, call 1-888-853-4656 to determine eligibility or visit www.tamarisstudy.com.

Today's research touches our future, and there is a possibility that the information obtained in this study may help in the development of a new therapy for those who suffer from critical limb ischemia with foot or leg ulcers.

For more information, contact Hal Coxon at 847-919-1005 or halcoxon@axmarketing.com.

[Text from file received from Hal Coxon, Axiom Accelerated Clinical Patient Recruitment]

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