Cronkite died at 7:42 p.m. with his family by his side at his Manhattan home after a long illness, CBS vice president Linda Mason said. Marlene Adler, Cronkite's chief of staff, said Cronkite died of cerebrovascular disease.
Morley Safer, a longtime "60 Minutes" correspondent, called Cronkite "the father of television news."
"The trust that viewers placed in him was based on the recognition of his fairness, honesty and strict objectivity ... and of course his long experience as a shoe-leather reporter covering everything from local politics to World War II and its aftermath in the Soviet Union," Safer said. "He was a giant of journalism and privately one of the funniest, happiest men I've ever known."
Cronkite was the face of the "CBS Evening News" from 1962 to 1981, when stories ranged from the assassinations of President John F. Kennedy and the Rev. Martin Luther King Jr. to racial and anti-war riots, Watergate and the Iranian hostage crisis.
It was Cronkite who read the bulletins coming from Dallas when Kennedy was shot Nov. 22, 1963, interrupting a live CBS-TV broadcast of the soap opera "As the World Turns."
He died just three days before the 40th anniversary of the moon landing, another earthshaking moment of history linked inexorably with his reporting.
"What was so remarkable about it was that he was not only in the midst of so many great stories, he was also the managing editor of CBS News and the managing editor for America," former NBC News anchor Tom Brokaw said. "Walter always made us better. He set the bar so high."
Cronkite was the broadcaster to whom the title "anchorman" was first applied, and he came so identified in that role that eventually his own name became the term for the job in other languages. (Swedish anchors are known as Kronkiters; In Holland, they are Cronkiters.)
"He was a great broadcaster and a gentleman whose experience, honesty, professionalism and style defined the role of anchor and commentator," CBS Corp. chief executive Leslie Moonves said in a statement.
CBS has scheduled a prime-time special, "That's the Way it Was: Remembering Walter Cronkite," for 7 p.m. Sunday.
President Barack Obama issued a statement saying that Cronkite set the standard by which all other news anchors have been judged.
"He invited us to believe in him, and he never let us down. This country has lost an icon and a dear friend, and he will be truly missed," Obama said.
His 1968 editorial declaring the United States was "mired in stalemate" in Vietnam was seen by some as a turning point in U.S. opinion of the war. He also helped broker the 1977 invitation that took Egyptian President Anwar Sadat to Jerusalem, the breakthrough to Egypt's peace treaty with Israel.
He followed the 1960s space race with open fascination, anchoring marathon broadcasts of major flights from the first suborbital shot to the first moon landing, exclaiming, "Look at those pictures, wow!" as Neil Armstrong stepped on the moon's surface in 1969. In 1998, for CNN, he went back to Cape Canaveral to cover John Glenn's return to space after 36 years.
"He had a passion for human space exploration, an enthusiasm that was contagious, and the trust of his audience. He will be missed," Armstrong said in a statement.
He had been scheduled to speak last January for the 50th anniversary of the U.S. Space & Rocket Center in Huntsville, Ala., but ill health prevented his appearance.
A former wire service reporter and war correspondent, he valued accuracy, objectivity and understated compassion. He expressed liberal views in more recent writings but said he had always aimed to be fair and professional in his judgments on the air.
Off camera, his stamina and admittedly demanding ways brought him the nickname "Old Ironpants." But to viewers, he was "Uncle Walter," with his jowls and grainy baritone, his warm, direct expression and his trim mustache.
When he summed up the news each evening by stating, "And THAT's the way it is," millions agreed. His reputation survived accusations of bias by Richard Nixon's vice president, Spiro Agnew, and being labeled a "pinko" in the tirades of a fictional icon, Archie Bunker of CBS's "All in the Family."
Two polls pronounced Cronkite the "most trusted man in America": a 1972 "trust index" survey in which he finished No. 1, about 15 points higher than leading politicians, and a 1974 survey in which people chose him as the most trusted television newscaster.
"He was the most trusted man in America and he was a reporter. Imagine. Who could we say that about today?" said Jeff Fager, executive producer of "60 Minutes," who began working at CBS News the year Cronkite stepped down from the anchor job.
Like fellow Midwesterner Johnny Carson, Cronkite seemed to embody the nation's mainstream. When he broke down as he announced Kennedy's death, removing his glasses and fighting back tears, the times seemed to break down with him.
And when Cronkite took sides, he helped shape the times. After the 1968 Tet offensive, he visited Vietnam and wrote and narrated a "speculative, personal" report advocating negotiations leading to the withdrawal of American troops.
"We have been too often disappointed by the optimism of the American leaders, both in Vietnam and Washington, to have faith any longer in the silver linings they find in the darkest clouds," he said, and concluded, "We are mired in stalemate."
After the broadcast, President Lyndon B. Johnson reportedly said, "If I've lost Cronkite, I've lost middle America."
In the fall of 1972, responding to reports in The Washington Post, Cronkite aired a two-part series on Watergate that helped ensure national attention to the then-emerging scandal.
"When the news is bad, Walter hurts," the late CBS president Fred Friendly once said. "When the news embarrasses America, Walter is embarrassed. When the news is humorous, Walter smiles with understanding."
More recently, in a syndicated column, Cronkite defended the liberal record of Democratic presidential candidate John Kerry and criticized the Iraq war and other Bush administration policies.
But when asked by CNN's Larry King if that column was evidence of media bias, Cronkite set forth the distinction between opinion and reporting. "We all have prejudices," he said of his fellow journalists, "but we also understand how to set them aside when we do the job."
Cronkite was the top newsman during the peak era for the networks, when the nightly broadcasts grew to a half-hour and 24-hour cable and the Internet were still well in the future.
As many as 18 million households tuned in to Cronkite's top-rated program each evening. Twice that number watched his final show, on March 6, 1981, compared with fewer than 10 million in 2005 for the departure of Dan Rather.
Rather, who replaced Cronkite at the anchor desk, called Cronkite "a giant of the journalistic craft."
"Walter loved reporting and delivering the news, and he was superb at both," he said. "He deserves recognition and remembrance, too, for the way he solidly backed his correspondents and producers, defending them vigorously in coverage of difficult stories such as the Vietnam War and the Watergate crimes."
A vigorous 64 years old, Cronkite had stepped down with the assurance that other duties awaited him at CBS News, but found little demand there for his services. He hosted the shortlived science magazine series "Walter Cronkite's Universe" and was retained by the network as a consultant, although, as he was known to state wistfully, he was never consulted.
