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The Astros loaded the bases and took their first lead of the season when Placido Polanco bobbled Tommy Manzella's sharp grounder to third, allowing Lee to score on the infield single.
Chris Sampson relieved Paulino before the sixth inning. Paulino threw 110 pitches.
NOTES: Phillies closer Brad Lidge allowed four runs and three hits for Class-A Clearwater against Dunedin, his first rehab outing since elbow surgery. Lidge threw 20 pitches and retired only two batters. Left-hander J.C. Romero, also coming off elbow surgery, threw a scoreless inning in the same game with two strikeouts. ... The Astros and Phillies wore throwback uniforms commemorating the first regular-season game played at the Houston Astrodome, on April 12, 1965. Philadelphia won that one 2-0. ... All-Star slugger Lance Berkman will skip Houston's first road trip to get more treatment on his injured left knee. The team said Berkman will work with physical therapist Matt Holland in Houston while the Astros visit St. Louis and Chicago next week. Berkman had arthroscopic surgery on March 13 and has been on the disabled list since March 31.
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