It was the most extensive operation yet and the 11th known face transplant worldwide.
During the 24-hour surgery, doctors lifted an entire face, including jaw, nose, cheekbones, muscles, teeth and eyelids, and placed it masklike onto the man, Dr. Joan Pere Barret told The Associated Press on Friday.
Transplant experts hailed the surgery, carried out late last month at Barcelona's Vall d'Hebron Hospital, as a significant advance.
"It is a breakthrough. They are pushing the envelope and I am very happy for them," said Dr. Thomas Romo, chief of facial and reconstructive surgery at Lenox Hill Hospital in New York.
The Spanish patient, who was not identified, now has a completely new face from his hairline down and only one visible scar, which looks like a wrinkle running across his neck, said Barret, who headed the 30-member surgical team.
The man cannot yet speak, eat or smile, but he can see and swallow saliva, the surgeon said. He is expected to be able to eat and breathe on his own in about a week.
"If you look him in the face, you see a normal person," Barret said. "He sits up, he walks in his hospital room and he watches television."
Before the transplant, the 30-year-old patient had had nine surgeries and could only breathe with the help of a ventilator and get nourishment from a feeding tube. He also had problems speaking.
The 2005 accident, in which he shot himself with a shotgun, essentially destroyed his face from the eye sockets down, although his eyes and eyesight were unaffected.
During the daylong operation, Barret said his team cut off the donor's face below the eye sockets and attached the bone structure along with muscles and nerves to the recipient "in one piece."
"Imagine a skull. It is as if with a saw, we cut everything just below the upper part of the eye sockets, as if we were sawing all that," he said. Then, "everything attached to the mask is placed on the recipient."
"It is a little bit like the movie with John Travolta and Nicolas Cage," the surgeon said, referring to the 1997 thriller "Face/Off", in which the face of the character played by Cage is grafted onto the Travolta character's skull in an identity switch.
Face transplants in the real world have gained acceptance since the first partial transplant almost five years ago in France. Patients don't look like the dead people whose skin and facial features they now live with. And skeptical bioethicists and doctors groups have warmed to the idea for patients who have tried reconstructive surgery with little success.
There have been 10 partial transplants worldwide, including in the United States, China and elsewhere in Spain, but this is the first full face transplant, Barret said.