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The Astros added on in the third inning. Cubs reliever Mitch Atkins walked Jeff Keppinger and gave up a single to Johnson before Castro homered to right. It was his second of the season and gave Houston an 8-0 lead. It was the first home run by a Houston catcher that drove in at least three runs since Brad Ausmus hit a grand slam in Aug. 5, 2006, at Arizona.
Geovany Soto scored on Colvin's groundout in the third inning.
Derrek Lee doubled in the fourth inning and went to third on a wild pitch then scored on Ramirez's sacrifice fly.
Colvin led off the sixth with his 13th homer of the season. One out later, Lee doubled and Ramirez followed with a two-run homer to get to 8-5.
But Johnson put an end to a potential Cubs rally with a two-run line drive to right for his first home run of his career in the seventh and had an RBI triple in the eighth.
NOTES: The Astros will recall Wesley Wright from Triple-A Round Rock before Tuesday night's game against the Cubs. Wright is scheduled to make his first career start. Earlier in the season, Wright pitched out of the bullpen for Houston. He allowed six runs over 9 2-3 innings in six relief appearances without a decision. ... Castro ended the night with two errors at shortstop for the Cubs. ... Sanchez had hits. He has 17 career hits and his last multihit game was also a three hit game on Oct. 1, 2006, at Detroit while with the Royals.
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