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It will take further work to see if the initial promise is borne out, Wernig said. If so, it would be the first practical method for generating iPS cells that could be used for transplant therapies, he said.
"If it turns out to be a very efficient way of generating iPS cells without any genetic modification, then it would be a big advance," Wernig said.
Kathrin Plath of the University of California, Los Angeles, called the work "very impressive" and said it appears to show the best approach so far for making such cells for transplant tissue.
"We will definitely try this method here at UCLA," she said in an e-mail.
Still, further study is needed to confirm the benefits of the new approach, she said.
Cell Stem Cell:
Information on iPS cells: http://bit.ly/dvGaqN
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