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The Giants added a run in third after Aubrey Huff led off with a double and advanced to third when the Rockies botched a rundown. Pat Burrell followed with a sacrifice fly.
De La Rosa allowed four hits, five walks and three runs in six innings.
Matt Reynolds gave up a homer to Ross, his 14th of the season, with one out in the seventh.
NOTES: Olivo left in the ninth when shortstop Tulowitzki came running across the diamond to catch Cain's popup between the mound and first base and clipped Olivo in the head or neck with his right leg. ... Flulike symptoms kept Rockies third baseman Ian Stewart from making his first start since Aug. 25. He has played in two games since returning Sept. 23 from a right oblique strain. ... Giants outfielder Andres Torres was not in the lineup. He made his first start Saturday since returning from an appendectomy Sept. 11 and homered but experienced irritation around the incision later in the game. ... Rockies 2B Eric Young Jr. was in the lineup after leaving with a bruised neck in the second inning Saturday night. ... Cain pitched one-hitters on May 21, 2006, at Oakland, and May 28 this season against Arizona.
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