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An upset Latos was yelling at someone in the dugout after the inning.
San Diego's Nick Hundley tied it at 2 with a 398-foot home run on a full-count pitch from Dempster into the second deck in left field, his eighth. Chase Headley was aboard on a one-out walk.
Moments after homering, Hundley tried to calm down Latos in the dugout.
At nearly the exact moment Hundley connected, Juan Uribe hit a trying solo home run leading off the fourth to pull the Giants into a 2-2 tie.
Dempster allowed four hits and walked two. The Padres had two runners on and no outs in the seventh before Dempster struck out the side.
NOTES: Padres OF Will Venable missed his second straight start with a sore lower back, similar to the injury that landed him on the DL earlier this season. ... San Diego RHP Chris Young is scheduled to make his fourth start of the season Wednesday night, his third since returning from a five-month stay on the DL. The Cubs' scheduled starter is Randy Wells. ... Dempster struck out nine for the fifth time this season. He became the third Canadian-born pitcher with at least three 15-win seasons. The others are Fergie Jenkins (10) and Russ Ford (3). ... The Cubs, fifth in the NL Central, improved to 16-8 in September.
[Associated Press;
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