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Holliday hit a low liner that skimmed over the wall in right-center in the eighth, a solo homer that put St. Louis ahead 3-2.
Chris Carpenter made his fifth opening day start for St. Louis and worked seven stingy innings, allowing two runs on only two hits. Tim Stauffer, standing in for injured Mat Latos, allowed two runs on nine hits in six innings for San Diego.
The Cardinals outhit San Diego 10-2 the first six innings but hit into three double plays, two by Pujols, and were 2 for 9 with runners in scoring position. Three times they put the first two men on, but totaled one run.
The Padres erased their second one-run deficit on Hundley's two-out, RBI double in the fifth. The Cardinals almost made it out of the inning the previous at-bat when Maybin struck out with Ryan Ludwick running on a full count.
Ludwick looked like an easy out at second, but he rattled the ball out of second baseman Skip Schumaker's glove, what Schumaker called a "perfect knockdown," for a stolen base.
New Cardinals right fielder Lance Berkman, a regular outfielder for the first time since 2004, had two hits and didn't touch the ball in eight innings in the field.
NOTES: Jim Edmonds, who ditched a comeback bid in February after signing a minor league contract with the Cardinals, threw out the first pitch. ... Latos, who's on the 15-day DL, threw a bullpen session as scheduled prior to the game. ... Cardinals INF Nick Punto was placed on the 15-day DL retroactive to March 22 with a sports hernia. He's with the team and could play by May.
[Associated Press;
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