Paul Konerko had two singles for a quiet White Sox offense in his first start since Sunday. He missed the three previous games with bruised left leg.
"Hitting-wise I felt not bad," Konerko said. "I felt maybe 80 or 90 percent. Definitely, for the most part, could do what I wanted to do."
Adam Dunn homered in the ninth, a possible good sign for the struggling slugger, though it came with his club six runs down.
"Yeah, I mean they feel good, it's just meaningless," Dunn said. "Personally it felt good, but it meant nothing, had no impact on the game."
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Humber (8-8) lost his fourth straight start. He went 6 1-3 innings, allowing five hits and four runs.
Entering the game, the players currently on the Yankees' were a combined 0 for 18 lifetime against Humber. He retired the first four batters on Thursday before Cano came up in the second.
With one out in the inning, Cano lined the first pitch he saw from Humber into the left-field bullpen for the first run of the game. It was Cano's 18th homer of the season and second in as many games after he'd gone 14 games without a longball.
Nova had good stuff early, retiring the first seven White Sox in order, the last three on strikeouts.
The streak was broken when Alejandro De Aza beat out an infield grounder to shortstop Derek Jeter. That gave De Aza, who was 4 for 4 in Wednesday's 18-7 loss to New York, five straight hits.
De Aza then stole second, went to third on Brent Morel's single to right and scored on Juan Pierre's sacrifice fly for a 1-all tie.
The Yankees regained the lead in the sixth thanks to the speed of Brett Gardner, who started the inning with a double to right and went to third on Jeter's sacrifice bunt.
Curtis Granderson hit a hard grounder to Dunn at first base and Gardner broke for the plate. Dunn stepped on the bag to retire Granderson and threw home, but Gardner slid home safely just ahead of the tag by catcher A.J. Pierzynski.
"I thought after Robbie's home run, we manufactured runs well," Girardi said. "Gardy starts with a double, Chief moves him over. Great baserunning by Gardy, the speed to score. I thought we manufactured well tonight."
Humber seemed to tire in the Yankees' two-run seventh. Cano led off with a single, Nick Swisher walked and Jorge Posada hit an RBI single for a 3-1 lead.
That was it for Humber, who was replaced by Jesse Crain after throwing 94 pitches. Swisher scored on Martin's sacrifice fly to deep center.
Next up is the Yankees' biggest rival, Boston, in a park New York has struggled in this season. Girardi says it's gratifying to enter the series in a dead heat.
"I think it says that we've been playing well," Girardi said. "We've been chasing them for awhile now. It just says a lot about this club and what we've been through. We've overcome some things. It is significant."
NOTES: Konerko had been out since being hit in the left knee by a pitch against Boston last Sunday. Manager Ozzie Guillen said Konerko would be limited to designated hitter duty for a few days. Bartolo Colon will start for the Yankees in the series opener against Jon Lester. New York is 454-458 all-time at Fenway. However, the Yankees are 1-8 vs. Boston this season and have lost seven straight at Fenway. Colon has lost both of his starts against the Red Sox this season, once each at Boston and New York. Mark Buehrle gets the call for the White Sox in their opener at Minnesota in a key series for two teams scrambling to stay in the AL Central race. The Twins have beaten the White Sox in seven of eight meetings this season and have won 29 of their last 36 against Chicago. Buehrle has posted a 2.03 ERA over his last eight starts but is just 2-1 over that stretch. He's allowed three runs or less in 16 straight starts. ... White Sox speedster Juan Pierre was thrown out stealing in the sixth. He's just 16 for 29 on the basepaths this season.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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