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Washington then intentionally Darwin Barney with the pitcher on deck, but Lopez singled to center. The slow-running Soriano was unable to score on the play, leaving the bases loaded for Castro, the NL hits leader. Castro struck out, ending the threat.
Johnson led off the fifth with his fifth homer, putting the Cubs up 3-1.
"I kind of rolled a couple through the hole early and it started to relax me a little bit," Johnson said.
Werth responded with his 14th homer, a drive into the bleachers in left-center in the sixth. That was it for Lopez, who departed after 89 pitches.
"There are times when you want to get a guy out of there when he's feeling good about himself," Quade said. "After the home run, it was a little earlier than I wanted to go to (reliever Jeff) Samardzija, but it happens."
Detwiler was pulled after throwing 84 pitches. Nationals manager Davey Johnson gave him passing marks, but just barely, noting Detwiler had only been starting for a short while.
"He's been in the bullpen," Johnson said. "I give him a C-plus for tonight. The two ballparks he's pitched in lately, you have to be perfect, you can't make any mistakes. He minimized the damage tonight."
Soriano connected against Collin Balester with one out in the sixth, hitting a drive to left-center for his 20th homer. Soriano has homered at least 20 times in 10 straight seasons, joining St. Louis' Albert Pujols and Boston's David Ortiz as the only players to reach that mark in each season of the last decade.
"I'm very proud of myself because I work hard and try to be consistent in this game," Soriano said. "I never expected to hit 20 home runs in this game but I did. I think it's because of the hard work and concentration and the love that I have for the game."
NOTES: After being a late scratch Tuesday because of back spasms, Cubs 3B Aramis Ramirez returned to the lineup. Quade didn't issue a lineup until after Ramirez went through pregame batting practice. Once he completed that with no complications, he was cleared to play. Ramirez leads all major league players with 15 home runs since June 25. ... Davey Johnson said of ailing catcher Ivan Rodriguez, "He's not doing too well. He's pushing it too hard and he's had a setback." Rodriguez has been on the disabled list since July 7 with a strained right oblique. There is no current timetable for his return. ... The Cubs and Nationals wrap up their three-game series Thursday afternoon in a makeup of Monday's rainout. Ryan Dempster will look to continue his solid pitching of late in his start for the Cubs. He is 5-3 with a 3.26 ERA over his last 12 starts. Jordan Zimmermann will take the mound for Washington. Zimmermann has a 6.35 ERA in his two career starts against Chicago. ... The Cubs unveiled a statue of longtime third baseman and broadcaster Ron Santo in a ceremony before Wednesday's game. The statue depicts Santo making a throw and is place in the plaza on the southeast corner outside Wrigley Field. ... Castro's streak of scoring a run in 10 straight games came to an end. The last Cub to score 11 games in a row was Rick Monday in 1976.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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