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The White Sox have lost seven straight at U.S. Cellular Field and 13 of their last 17. Chicago fell five games behind Detroit in the AL Central.
Butler's two hits came on the heels of his 1-for-15 series at Tampa Bay. Butler has hit eight of his 14 home runs in the month since the All-Star break.
"That was good," Butler said. "Got a pitch out over the plate and didn't miss it. Squared it good and it got up."
Chen walked three batters and hit two more combined in the first three innings.
Alex Rios ended both the first and third by flying out with the bases loaded. Rios, who entered the game hitting .170 in 94 at-bats with runners in scoring position, was loudly booed after each plate appearance.
"We were one hit away from getting something going," Guillen said. "Alex was the hitter and he couldn't get it done."
After the White Sox were unable to take advantage of Chen's early wildness, he recovered to retire the last seven batters he faced and 10 of the final 11.
Brent Morel was the only base-runner in that stretch, reaching on a double error in the fourth. Chen appeared to have struck out Morel with an 0-2 pitch was called for a quick pitch, an automatic ball.
"When Bruce is on his game, he pitches good against just about everybody," Yost said. "Bruce has been the winningest pitcher we've had here the last two years. It's because he's crafty, he doesn't give in, he changes speeds, keeps the ball down."
NOTES: Jake Peavy will start for Chicago on Saturday against Kansas City's Luke Hochevar. Hochevar is 4-0 over his last eight starts, with the Royals going 7-1 in those games. Peavy has dropped four of his last five decisions. ... White Sox C A.J. Pierzynski had to leave the game after being hit on the left wrist by a pitch in the third. X-rays on the injury were negative and he's listed as day-to-day. ... Chicago's Carlos Quentin was hit by a pitch in the first inning. It was the 23rd hit by pitch for Quentin this season, tying a White Sox record set by Minnie Minoso in 1956.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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