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"A big win feels good," Pujols said. "I don't know what it is, over the last two or three road trips, we haven't started our road trips the way we wanted to. But it feels good to get a win tonight."
Pujols has homered three times this season off Lopez after entering the season 0 for 11 against the veteran righty.
Jake Westbrook (10-7) held the Cubs to seven hits and two runs in seven innings, beating Chicago for the first time in three starts this season.
Aramis Ramirez had two hits and drove in both Chicago's runs. He had a double and run-scoring single and is hitting .487 (19 for 39) with four homers and 12 RBIs in his last nine games.
He added a sacrifice fly in the fifth, cutting the Cardinals' lead to 3-2, but it wasn't enough on a night when Lopez couldn't keep the ball in the park.
NOTES: RHP Dillon Maples, the Cubs' 14th-round pick in the most recent draft, made his first appearance at Wrigley Field since signing with the club last Tuesday. The Cubs signed Maples away from the University of North Carolina, where he was to play both baseball and football, for a $2.5 million signing bonus, the most ever given to a player taken after the third round. Cardinals SS Rafael Furcal was held out of the lineup for the second straight day after jamming his right thumb during batting practice on Saturday. 2B Ryan Theriot was left out of Sunday's starting lineup because of hamstring tightness. Both players are listed as day-to-day. Cubs RHP Andrew Cashner will take the next step in his rehab process when he takes the mound for Double-A Tennessee on Tuesday. Cashner has been out with a strained right rotator cuff since his start for the Cubs on April 5, his only game action this season. The Cubs will start Ryan Dempster in the opener a four-game home series against Atlanta on Monday. Jair Jurrjens will pitch for the Braves. Dempster is just 2-11 in his career against the Braves. St. Louis returns home Monday for the first of three games against the Dodgers. The Cards will send Chris Carpenter to the mound against LA's Nathan Eovaldi. Carpenter has won all six of his career decisions against the Dodgers.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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