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Brett Wallace led off the fourth inning with a solo homer off Carlos Zambrano to give the Astros a 1-0 lead.
Zambrano settled down to retire the next 11 batters, including six by strikeouts. The streak was broken up by Lyles' first career hit, a soft single under the glove of first baseman Carlos Pena.
Wallace's home run was the lone blemish on Zambrano's outing. The righty allowed seven hits over eight innings and struck out seven.
Lyles ran into trouble in the fifth inning when Blake DeWitt's leadoff pop-up to shallow left field fell to the ground untouched in a moment of miscommunication between shortstop Clint Barmes and left fielder Carlos Lee. DeWitt was credited with a double and advanced to third on a Tony Campana sacrifice bunt.
But the righty promptly struck out Soto and Zambrano to end the threat. Zambrano broke his bat over his knee out of frustration after going down swinging.
Lyles, the youngest active player in the Major Leagues at 20 years and 224 days, surrendered his first hit to Starlin Castro, the second youngest player in the majors. Castro, who turned 21 on March 24, tripled to right field in the first inning but failed to score. Lyles struck out Castro in his next at-bat.
NOTES: Astros OF Jason Bourgeois (strained left oblique) took live batting practice Tuesday and is scheduled to play rehab games Thursday through Saturday with Triple-A Oklahoma City if all goes well. ... RHP Brandon Lyon (right biceps tendinitis and rotator tear) is scheduled to throw a simulated game Thursday in San Diego. ... Cubs RHP Matt Garza (elbow) is doubtful for a return this weekend at St. Louis, as the club initially hoped for. Manager Mike Quade said the team wants to play it safe and give Garza an extra side session. He will be able to start during the Cincinnati series June 6-8.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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