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Brad Penny (5-4) rebounded from a shaky first inning to pick up the victory. He allowed three runs and eight hits, struck out five and walked two in five innings.
Three relievers combined for four innings of two-hit ball after Penny departed. Closer Jose Valverde got Konerko to line out with runners on first and second to end the game.
"Peavy's real tough, obviously," Tigers manager Jim Leyland said. "You're not gonna get a whole lot, so when we got the opportunity, we came up with a big one. It didn't start off too good, but it ended up good."
Since being traded to the White Sox on July 31, 2009, Peavy is 12-7 in 27 starts. He was bothered by ankle problems in 2009 and went 3-0 in three late starts for the White Sox. He made 17 starts last year and was 7-6 before his season was cut short by the shoulder injury.
Cabrera hit his 13th homer off Will Ohman in the sixth. He also had a tiebreaking two-run homer in the ninth inning of Saturday's 4-2 win.
Konerko was back in the lineup after having a minor procedure to dislodge a loose fragment in his left wrist on Friday. He hit an RBI double in Chicago's two-run first.
White Sox second baseman Gordon Beckham homered for the second straight day. His solo drive in the fourth was his sixth of the season.
Adam Dunn was 1 for 4 with three strikeouts for Chicago. He struck out in the eighth, igniting boos from the crowd.
NOTES: White Sox manager Ozzie Guillen gave CF Alex Rios the day off. He is in a 6-for-40 slump covering his last 10 games. Guillen said he might also rest Rios on Monday against the Mariners. ... The White Sox activated INF Mark Teahen from the 15-day DL and designated RHP Jeff Marquez for assignment.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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