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Stafford was 28 of 50 for 293 yards and two TDs. He was sacked in the end zone for a safety in the second quarter.
"Matt didn't have a whole lot of time today," Schwartz said. "We had a hard time getting the run game going. When it's one-dimensional that way, and I think it was, you're going to have a difficult time."
Detroit ran for only 66 yards.
Jason Hanson missed a 52-yard field goal attempt that would've given Detroit a four-point lead late in the first half, then Akers made a 55-yard kick. That put the 49ers ahead 12-10 as time expired in the half.
In the fourth, Stafford connected with Nate Burleson on a 5-yard pass into the end zone that was ruled incomplete on the field. It was overturned after video review, giving Detroit a 19-15 lead. Burleson caught the ball and got both feet down, then lost the ball after tumbling beyond the end zone -- a play similar to Calvin's Johnson's well-documented play in the end zone that was ruled incomplete last year at Chicago.
The Lions couldn't hold the lead and were left to rue a couple trips deep into San Francisco territory that ended with short field goals -- one in the first quarter and another in the third.
"We're not going to go 16-0," Schwartz said. "We have to protect the quarterback better, have to run the ball better, make more plays down the field. We have to stop the run better, we have to convert field goals."
The 49ers overcame 15 penalties, including five false starts at raucous Ford Field.
"Once you get a couple false starts, it's like throwing gasoline on a fire," Smith said.
NOTES: San Francisco and Chicago combined for 14 false starts at Detroit, matching Houston's record from 2004 for the most false starts by visiting teams in back-to-back games since 1991, according to STATS LLC. ... Harbaugh played for Baltimore in 1998, when Schwartz was a Ravens assistant.
Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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