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Isringhausen gave up five hits and five runs (all earned), in two-thirds of an inning.
"The stuff was there," Angels manager Mike Scioscia said. "(Isringhausen) just had the ball up."
Cubs left-hander Chris Rusin worked 5 1/3 scoreless innings. He allowed two hits and struck out three against an Angels lineup that featured regulars Kendrys Morales, Mark Trumbo, Maicer Izturis, Alberto Callaspo and Bobby Abreu.
Izturis hit his first homer of the spring in the eighth.
Castro and David DeJesus each had two of the Cubs' 13 hits. Callaspo had two of the Angels' five hits.
Cubs right-hander Matt Garza worked four scoreless innings in a minor league game Sunday. Garza allowed two hits and struck out six and threw 51 pitches before finishing his work in the bullpen.
Garza is 2-2 with a 5.51 ERA over 16 1/3 innings and five starts this spring.
Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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