Southern Marin fire Battalion Chief Matt Barnes said the unidentified pair and a third fisherman were pulled into the frigid waters on Friday just before 5 p.m.
The trio was on a rocky coastline just northwest of the bridge in the Marin Headlands, which is exposed to large swells rolling in from the Pacific.
The third man managed to make it back to shore and flagged down bystanders, who called 911.
The two were plucked from the water about 100 yards offshore by a Tiburon Fire Department boat and the Coast Guard.
The Marin County Coroner's Office is investigating the deaths.
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