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Freshman Stilman White is the only true point guard left on the roster, while versatile senior Justin Watts will likely see time at the point if Marshall can't play.
"He just doesn't make bad decisions, he doesn't take bad shots," Creighton coach Greg McDermott said of Marshall. "He's in total control."
Doug McDermott scored 20 points for the eighth-seeded Bluejays (29-6), who fell behind by 15 in the first half and trailed by 19 after halftime. North Carolina shot 51 percent and never let Creighton's offense build similar momentum.
For Xavier, Tu Holloway added 21 points for Xavier, which edged Notre Dame in its tournament opener then took out the sentimental favorite.
Lehigh was a No. 15 seed that had upset No. 2 seed Duke on Friday night, a performance that turned a building full of light blue-wearing UNC fans into Lehigh supporters after the Mountain Hawks (27-8) had taken out the Tar Heels' biggest rival. The crowd hadn't forgotten, either, cheering the Lehigh players when they took their seats during the Creighton-North Carolina game.
Lehigh led by 15 midway through the first half and 37-33 at the break, but Xavier's defense took over after halftime. Lehigh shot just 5 for 34 (15 percent) in the second half as the Musketeers pushed ahead.
"We were doing a terrible job of containing the basketball," Xavier coach Chris Mack said. "We were helping up on penetration. And it didn't matter how effective we were going to be on the offensive end, if we weren't going to get stops, we weren't going to have a chance to win."
The Musketeers won despite playing most of the game without their third-leading scorer, Dezmine Wells. He injured his right toe in the first half and did not return.
The loss ended a memorable few days for the Mountain Hawks in the program's fifth NCAA appearance.
"I never imagined us playing here playing against these top-tier type of teams," Lehigh guard B.J. Bailey said. "I'm really amazed and proud of our team for us to be here right now. Definitely didn't imagine that, but I'm happy we're here now and we had the chance. Not everybody gets to do this type of stuff, so I'm happy."
Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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