The state-run TV says the suicide attacks occurred as worshippers were leaving a mosque following Friday prayers in the city of Daraa, south of Damascus.
It was not immediately clear how many people were killed or wounded in the attacks.
Syrian TV blamed fighters with Jabhat al-Nusra, a group the U.S. has declared a terrorist organization.
Daraa is the birthplace of the uprising against President Bashar Assad that erupted nearly two years ago.
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