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 Ryan Dempster (4-6) got his 2,000 career strikeout when he fanned Alberto Callaspo to open the sixth.
The Red Sox took two of three in the weekend series against the Angels and have won six of eight.
Los Angeles entered the weekend having won eight straight against the Red Sox after going 6-0 last season, but dropped the final two after winning the opener of a day-night doubleheader Saturday.
Albert Pujols and Callaspo each had solo homers for the Angels.
Ortiz, who hit a two-run homer and drove in three runs in Boston's 7-2 win in the nightcap of a doubleheader Saturday, has five homers and 14 RBIs in his last 10 games.
Saltalamacchia and Carp opened the sixth with homers into the center field seats off starter Joe Blanton (1-10), Carp's drive chasing Blanton. In the next inning, Saltalamacchia homered to center field again, this time a three-run shot into the first row off Robert Coello to give Boston a 10-3 lead.
Dempster gave up three runs on six hits in six innings, walking two and striking out six for just his second victory in his last six decisions.
Blanton was tagged for seven runs -- six earned -- with three homers in eight hits over five-plus innings.
Trailing 1-0 in the third, the Red Sox scored four runs off Blanton. Daniel Nava tied it with an RBI single, Dustin Pedroia singled, then Ortiz belted his homer into the Red Sox bullpen to make it 4-1.
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Callaspo hit a solo homer in the fourth, but Jacoby Ellsbury's RBI triple into the right field corner made it 5-2.
Los Angeles cut it to 5-3 in the fifth on Mark Trumbo's run-scoring single after Mike Trout doubled off the Green Monster.
Pujols' solo homer pushed the Angels ahead in the first.
NOTES: Saltalamacchia had his fourth two-homer game, his previous was April of last season at the Chicago White Sox. ... Pedroia and teammate Jose Iglesias both extended hitting streaks to 13 games, with Iglesias' being a career high. ... Blanton entered the game having allowed the most hits in the majors. ... Dempster entered 0-2 with 17 runs in 13 2-3 innings in his career against Los Angeles. ... The Angels' Howie Kendrick came in 12 for his last 16, but went 0 for 4. . ... Boston is a majors' best 13-6 in day games. ... Boston manager John Farrell said before the game that RHP Clay Buchholz was "sore," but still needed to be examined. Buchholz left Saturday's second game with what the team called "neck tightness." ... Josh Hamilton went 0 for 5 with two strikeouts. ... The Angels are scheduled to open a three-game series in Baltimore Monday with Jered Weaver (1-1, 3.13) facing the Orioles' Freddy Garcia (2-3, 4.470 ERA). ... Boston plays at the Tampa Bay Rays Monday with John Lackey (3-5, 2.79 ERA) slated to face Alex Cobb (6-2, 2.39 ERA).
[Associated
Press; KEN POWTAK]
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