Novartis' Gilenya fails in study for a type of MS

Send a link to a friend  Share

[December 01, 2014] ZURICH (Reuters) - Novartis AG said on Monday its drug Gilenya failed to meet its main goal in a late-stage study as a treatment for primary progressive multiple sclerosis (PPMS).

Results of the Phase III trial involving 970 people found Gilenya, also known as fingolimod, did not show a significant difference to placebo on a combination of disability measures.

There are currently no approved treatments for PPMS, a disorder of the central nervous system characterized by a steady worsening of neurologic functioning over time. It affects around 10 percent of the 2.3 million people diagnosed with multiple sclerosis worldwide.

Gilenya is already approved in the United States and Europe as a treatment for multiple sclerosis. The drug is being tested in Phase III trials as a treatment for pediatric MS and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).

(Reporting by Caroline Copley; Editing by Gopakumar Warrier)

[© 2014 Thomson Reuters. All rights reserved.]

Copyright 2014 Reuters. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

< Recent articles

Back to top