Amgen, Sanofi, Ono link with academia on proteins project

Send a link to a friend  Share

[October 28, 2014]  LONDON (Reuters) - U.S.-based Amgen, France's Sanofi and Ono Pharmaceutical of Japan have linked with three research institutes to study a super-family of proteins controlling everything from taste to the spread of cancer.

The decision by the three drugmakers to join forces with academia to generate high-resolution pictures of hundreds of proteins known as G-protein coupled receptors (GPCRs) is part of a growing trend to pool early-stage drug research.

GPCRs, which are implicated in many disease processes, are a hot topic of research and scientists working in the field were awarded the Nobel Prize for Chemistry two years ago.

GPCRs serve as a main conduit for chemicals to get past a cell's membrane. They are already highly valued as targets for drug interventions but mechanistically they are poorly understood.

Better information about their structure could help in the hunt for new drug candidates, the partners in the new GPCR Consortium believe.

The three collaborating academic research institutes are the iHuman Institute at ShanghaiTech University, Shanghai Institute of Materia Medica and the University of Southern California.

(Reporting by Ben Hirschler; Editing by David Holmes)

[ 2014 Thomson Reuters. All rights reserved.]

Copyright 2014 Reuters. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

[to top of second column]

< Recent articles

Back to top