Authorities said at a news conference Friday that DNA tests conducted on remains found by a utility worker last week less than a half-mile from where the child lived matched Caylee's genetic profile. But the only clue they give about her death is that her bones didn't suffer trauma, said Orange County medical examiner Dr. Jan Garavaglia.
"Bottom line is, folks, no child should have to go through this," said Orange County Sheriff Kevin Beary.
Without a definite cause of death, a defense lawyer can suggest to a jury that labeling Caylee's death a homicide is only speculation, said A. Russell Smith, a Jacksonville attorney and immediate past president of the Florida Association of Criminal Defense Lawyers.
"Juries are particularly conscientious in homicide cases because the penalties are so severe," Smith said. "So, to the extent that there are gaps in critical evidence, it makes the prosecutor's job much more difficult."
The discovery of the child's remains came after months of searches, twists and turns in the investigation. Casey Anthony was indicted in October on first-degree murder and other charges, even though no body was found. She has insisted that she left the girl with a baby sitter in June, but she didn't report her missing until July.
A search team said they did not check the wooded area sooner because it was submerged in water from the summer's heavy rains. But the utility worker who made the tip, Roy Kronk, said he had contacted the Orange County Sheriff's office in August to report that he had seen "something suspicious, a bag, in the same area."
The sheriff's office said he first called Aug. 11 to report the bag. A deputy responded but didn't find anything and was unable to locate him. Kronk called a crime hot line the following day and the information was passed on to the sheriff's office criminal investigation division. On Aug. 13, he called the sheriff's office a third time. He met a deputy, but authorities cleared the area as a place of interest in the search a short time later.
Beary said his department was investigating its response.
"If we missed a window of opportunity, we don't know," he said. "I'm not throwing anybody under the bus because we don't know."
It took authorities several days to analyze the remains since they were found last Thursday, and some are still undergoing tests. Some of the bones were as small as pebbles and had been scattered. Excavators searching on their hands and knees had a hard time finding the fragments.
Garavaglia - the star of cable TV's "Dr G: Medical Examiner - said authorities concluded Caylee was killed through DNA tests and "circumstantial evidence." She said she was certain this was a homicide, not an accidental death, and didn't expect further testing to reveal a specific cause.
"I wouldn't have issued the report if I wasn't sure," she said.
A jail chaplain told Casey Anthony that the remains were her daughter at the Orange County jail just before the news conference began. Her attorney, Jose Baez, was with her shortly after.