Speaking to radio station WJZD-FM in Gulfport, Miss., the former first lady said the comments she made about the state in the run up to the Iowa caucuses "were not exactly what I said," even though they came directly from an interview she gave to the Des Moines Register in October.
Clinton was on a campaign swing through Mississippi before Tuesday's Democratic presidential primary.
The newspaper quoted the New York senator discussing Iowa and Mississippi being the only states that have never elected a woman governor or sent a woman to Congress.
"How can Iowa be ranked with Mississippi? That's not what I see. That's not the quality. That's not the communitarianism; that's not the openness I see in Iowa," Hillary Clinton told the newspaper then
- a remark that prompted immediate criticism from Mississippi Republicans.
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Rival Barack Obama has been running radio ads in Mississippi calling Clinton's comments insulting to the state.
Friday, Clinton tried to downplay the remarks.
"What I said is what I learned is that neither Iowa or Mississippi had ever elected a woman statewide and I referenced the fact that I was the first woman elected statewide in New York and I told the Iowans that they had a chance to try to change that and now in Mississippi giving Mississippi voters a chance to change that," Clinton said in the radio interview.