Shortly before the crash Friday, the pilot radioed the nearby airport, warning that the plane was running out of fuel. Witnesses said the aircraft was flying low, then the electricity went out.
"The pilot issued a mayday," said Federal Aviation Administration spokesman Jim Peters. "The mayday was based on low fuel."
Officials initially said three people had died in the crash, but later revised the death toll to six. The Piper PA-34 crashed less than two miles from the Tri-State Airport near the Ohio and Kentucky state lines.
Peters said Tri-State controllers were working with the pilot when the plane made a sudden 180-degree turn and they lost contact.
FAA spokeswoman Arlene Salac didn't know where the plane had taken off from or where it was headed.
Witness Chris Smith was outside with his daughter when he saw the plane go down.
"It was flying way too low," he told The Herald Dispatch of Huntington. "It was flying so low I could have thrown a rock up and hit the bottom of the plane."
Smith's wife, Amanda, said she heard a loud crash and saw nearby power lines shake. Then the lights went out.
"My husband ran in with my daughter because they were sleigh riding and said,
'Call 911. A plane crashed,'" Smith told the newspaper.
Appalachian Power confirmed the plane hit a transmission line, but spokesman Phil Moye said power to the area was only briefly affected.
The National Transportation Safety Board will investigate the crash.
The plane is registered to Wilmington, Del.-based Wesvin Inc.