She detailed some of the cornerstone measures in her new government's platform, including an overhaul of the country's health care system, an increase in child subsidies and future tax cuts.
Merkel's Christian Democrats, their Bavarian-only sister party Christian Social Union and the pro-business Free Democrats came to a coalition agreement after nearly four weeks of negotiations following the Sept. 27 election.
Guido Westerwelle, the leader of the Free Democrats, said at a joint news conference with Merkel that the coalition agreement was "a great compass for our country."
He also said he wants all nuclear weapons to be pulled out of Germany, an issue that may prove vexing to the country's NATO allies, including the United States.
The coalition agreement is expected to be approved and signed on Monday.
The chancellor announced some new members of her new cabinet, while Westerwelle said he would present the Free Democrats' ministers to his party first and announce them later in the day to the public.
Westerwelle himself is expected to take over the posts of foreign minister and vice chancellor.
Merkel said that current Economy Minister Karl-Theodor zu Guttenberg will become the defense minister tasked with handling Germany's unpopular mission in Afghanistan. He replaces Franz Josef Jung, who is to take over at the Labor Ministry.
Germany's veteran interior minister, Wolfgang Schaeuble, was expected to take the key position of finance minister, a move that would put the 67-year-old member of Merkel's conservative Christian Democrats in charge of tending Germany's strained budget as her new government tries to balance tax cuts and fiscal discipline.
Ahead of Sept. 27 elections, both parties advocated tax cuts in an effort to spur economic growth. However, they differed on how far to go at a time when efforts to combat the economic crisis have pushed up debt.
Schaeuble is one of Germany's most experienced politicians. He has been interior minister since 2005 in Merkel's outgoing coalition of right and left, his second stint as the country's top security official.