The fallout from the ash cloud looming over Europe illustrates just how interconnected our world has become.
Thousands of planes fly millions of passengers and tons of cargo each day, providing the economic lifeblood of nations and businesses. The flights deliver products for sale or items as small as a specialized tool that lets a factory keep operating.
The planes also bring medicines to hospitals and food aid to earthquake or hurricane victims. And they bring war and peace. Soldiers are often transported to and from hot spots by air.
Tales of woe and inconvenience span every social level, from the Norwegian prime minister who got stuck in New York and had to govern using his iPad, to ordinary people who saved money for trips of a lifetime, then had to abandon those plans.
The eruption was a single act of nature, but it stopped the world in countless ways.
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A Texas mom stranded in Europe fears that the travel disruptions could force her to miss her son's wedding.
San Antonio native Nancy Price is due to fly from Bucharest to Munich, on to Chicago and then south to Texas for the Saturday nuptials in San Antonio. There's no other way for her to get home.
Planning for the wedding is further complicated because the couple is being married by Price's brother, Rev. Bert Clayton, a Methodist minister.
Clayton is in London with his wife. He's due to fly to the U.S. on Wednesday, so he's watching whether the travel disruption will continue.
Price has lived with her husband in a village north of Bucharest for the past 15 years. Ever the optimist, she says: "We are packing anyway."
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Marathoners train for months to be ready for race day. They're seasoned to overcome obstacles, but no one can outrun this volcano.
Many runners who have trained for Monday's Boston Marathon may not get the chance to compete after being stranded by flights that never left the tarmac. David Gray missed last year's race because of injury, and this was supposed to be the year he got the chance to climb Heartbreak Hill. Instead, he's stuck in hotel room in Brussels, Belgium.
"To have an act of God like this happen is really frustrating," Gray said.
A 41-year-old television producer from New York City who has run twice in the New York Marathon, Gray has tried everything: He's asked to be rerouted through Italy or Spain, figuring they were far enough south to avoid the ash cloud. But the only way he can get to those countries is by train or rental car, and they are all booked.
He's asked about flying out of Moscow, and going over the North Pole rather than the North Atlantic, but to no avail.
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Anissa Isker arrived at Charles de Gaulle Airport outside Paris in hopes of taking her son to Miami for specialized treatment that could help him walk. He has a rare genetic disease that keeps him in a wheelchair.
The hard-to-schedule treatment costs $3,000, a sum she is set to lose if they cannot leave this weekend. The French civil aviation authority is keeping airports in northern France closed until at least Saturday.
"When I told him we cannot leave, he got nervous, because he understood the situation," Isker said.
Across the Atlantic, Babafemi Adenuga faced a medical predicament of his own.
The family physician and medical professor at Howard University was supposed to lead a team of around 30 medical personnel to Nigeria to provide free care where it is badly needed.
But their flight to Nigeria connects in Frankfurt, and it was canceled because of the volcanic ash. Adenuga was scrambling Friday to get to Nigeria as soon as possible.
In Europe, potentially lifesaving organs were also stranded. A spokeswoman for the German Foundation for Organ Transplant said all organs that usually get flown out to patients were instead being distributed regionally.
With the airlines stalled, organs must now be delivered by land - and their recipients are chosen by distance.
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Oliver Dragojevic, a Croatian singer who has been hugely popular in the Balkans for 40 years, had a dream: To follow the steps of Sinatra, Clapton and Pavarotti and sing in the Royal Albert Hall.