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Three of the first four Pittsburgh batters of the game had hits against Lilly (1-2), but the Pirates got only one run, Bobby Crosby scoring on Jones' single.
The Pirates began the third with three straight doubles, taking a 3-0 lead when Andrew McCutchen and Jones drove in Andy LaRoche and McCutcheny.
Church's homer was on an 0-1 pitch to right with one out in the sixth. He has reached during all eight games he has appeared in at PNC Park this season.
Lilly was charged with four runs and nine hits with two strikeouts in six innings.
The Cubs' runs came in the fourth: Ramirez's sacrifice fly and Mike Fontenot's RBI single.
NOTES: Ramirez, batting .149 coming in, had batted third, fourth or fifth all season. ... The Pirates are 7-4 at home, 10-1 when scoring at least four runs and 9-0 when leading after four. ... Pittsburgh 1B Steve Pearce made his season debut after being recalled from the minors Tuesday. He went 0 for 3. ... Chicago OF Alfonso Soriano failed to tie a club record by homering in his fifth consecutive game. He went 1 for 4.
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