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Colts 38, Giants 14
INDIANAPOLIS (AP) -- Peyton Manning threw for three touchdowns in easily outplaying younger brother Eli.
In the second NFL meeting of siblings as starting quarterbacks, Peyton got lots of help from his running game and a Colts defense that was overrun last week against Houston. Joseph Addai rushed for 92 yards, Donald Brown added 69 and Indianapolis (1-1) forced Eli Manning to fumble twice, resulting in 14 points.
The brothers chatted in pregame warmups and twice shook hands at the coin toss. Then Peyton guided the Colts to a 24-0 halftime lead over the Giants (1-1), including a 98-yard drive capped by Dallas Clark's 50-yard TD catch.
Jets 28, Patriots 14
EAST RUTHERFORD, N.J. (AP) -- Mark Sanchez threw a career-high three touchdown passes, including two in the second half, and the Jets held on despite losing Darrelle Revis.
Six days after an awful outing in the opener against Baltimore, the Jets' offense was impressive as Sanchez completed a career-high 21 passes on 30 attempts for 220 yards and connected with Braylon Edwards, Jerricho Cotchery and Dustin Keller for scores.
The victory over the Patriots (1-1) ended a tumultuous week for the Jets (1-1), who were investigated by the NFL for the treatment of a female reporter at practice last weekend.
Revis, New York's All-Pro cornerback, left in the second quarter with a tight hamstring.
Packers 34, Bills 7
GREEN BAY, Wis. (AP) -- Clay Matthews had three sacks to lead Green Bay's dominant defense and Aaron Rodgers threw for two TDs and scrambled for another. Rodgers threw for 255 yards, with touchdowns to Donald Driver and James Jones. He also ran 9 yards for a score.
Linebacker Brandon Chillar and rookie safety Morgan Burnett intercepted Trent Edwards and the Packers (2-0) held the Bills (0-2) to 186 yards of total offense.
Edwards was 11 of 18 for 102 yards.
Eagles 35, Lions 32
DETROIT (AP) -- Michael Vick threw two touchdown passes in the first half in his first start in four years, and Philadelphia (1-1) held off a late rally.
LeSean McCoy gave the Eagles an 18-point lead with his third score with 6:17 left. The Lions (0-2) pulled within three points and recovered an onside kick with 1:50 left, but turned the ball over on downs without gaining a yard.
Vick, starting for Kevin Kolb (concussion), missed two seasons while serving an 18-month sentence for his role in a dogfighting operation and played sparingly last year. He hit 21 of 34 passes for 284 yards, ran for 37 yards and avoided losses with spin moves and slick steps.
Bengals 15, Ravens 10
CINCINNATI (AP) -- Mike Nugent kicked a career-high five field goals, two of them in the closing minutes.
Cincinnati (1-1) won the division by going 6-0 for the first time in franchise history. Nugent extended the Bengals' streak of division wins to a club-record eight.
The Ravens (1-1) couldn't pull one out despite another brilliant day by their defense, which hasn't allowed a touchdown in its past 10 quarters since the playoffs.
Chargers 38, Jaguars 13
SAN DIEGO (AP) -- Philip Rivers threw for 334 yards and three touchdowns and the Chargers (1-1) forced six turnovers by the Jaguars (1-1). Rookie running back Ryan Mathews hurt his right ankle in the second quarter and didn't return. He also fumbled for the second straight game, one of San Diego's three turnovers.
David Garrard was intercepted four times. The six giveaways tied Jacksonville's team record and led to 17 points for the Chargers.
Broncos 31, Seahawks 14
DENVER (AP) -- Kyle Orton threw for 307 yards and two TDs, and top draft pick Demaryius Thomas caught eight passes for 97 yards and a touchdown against Seattle (1-1).
The Broncos (1-1) won their 11th straight home opener and improved to 24-3 in home openers since 1984, the best mark in major professional sports during that span.
Thomas, who missed the preseason and last week's opener after aggravating his surgically repaired left foot during a scrimmage last month, hauled in Orton's 21-yard touchdown pass to make it 31-7 and cap his smashing debut.
Raiders 16, Rams 14
OAKLAND, Calif. (AP) -- Bruce Gradkowski replaced an ineffective Jason Campbell after halftime and led the Raiders to three scoring drives. Gradkowski threw a 4-yard touchdown pass to Louis Murphy, Darren McFadden ran for 145 yards and Sebastian Janikowski kicked three field goals to give Oakland (1-1) its first win in a home opener since 2004.
Sam Bradford threw two touchdown passes to Mark Clayton, but was unable to get the offense moving for much of the second half as the Rams (0-2) lost for the 27th time in 28 games.
Copyright 2010 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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