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"I felt strong and was making pitches, I just wasn't able to make any after that," Westbrook said. "It hurt us, hurt us big-time."
Westbrook had been 2-0 with a 2.37 ERA in his first three starts after the All-Star break.
Castro's RBI double over center fielder Jon Jay's head put the Cubs ahead. Carlos Pena drew a bases-loaded walk before Byrd finished the rally with a two-run single. Soriano, who hit a three-run homer in the first on Saturday, added a two-run drive for his 17th.
After managing just two hits off Dempster over the first five innings, the Cardinals climbed right back into it in the sixth on Berkman's league-leading 28th homer to straightaway center.
Carlos Marmol worked the ninth for his 20th save in 27 chances.
Eighth-place hitter Koyie Hill walked on a full count with one out in the sixth for the Cubs' first baserunner. Dempster's two-strike sacrifice bunt gave them their first runner in scoring position and Reed Johnson's sharp single to right with two outs ended the no-hit bid and put runners at the corners.
Daniel Descalso started at shortstop instead of Furcal, fatigued after a day of travel, plus just 6 for 38 for his career against Dempster, and made two exceptional plays early.
Descalso robbed Johnson to start the fourth on a grounder that deflected off third baseman David Freese's glove, then snared Soriano's grounder up the middle and made a strong throw to first from the grass to end the fifth.
NOTES: The crowd of 43,960 was the Cardinals' fifth sellout of the season. ... Pujols is 17 for 52 (.327) against Dempster with seven homers, 14 RBIs, 11 walks and one strikeout. ... The Cardinals also grounded into two double plays on Saturday. ... The Cubs are 16-29 against the NL Central.
[Associated Press;
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