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Anibal Sanchez left with the bases loaded and one out in the fifth, his shortest outing of the season, but reliever Edward Mujica turned pinch-hitter Jon Jay's comebacker into a double play.
The Marlins scored twice without a hit off Kyle McClellan in the third, parlaying walks to John Buck and Emilio Bonafacio, a failed bunt defense play to load them on Sanchez' comebacker, a wild pitch and Chris Coghlan's run-scoring groundout.
Florida opened a two-run fourth with four straight singles. Buck had two RBIs and Greg Dobbs one.
"It was just frustrating, a bunch of broken-bat hits and balls that weren't hit real hard," McClellan said. "You break a bunch of bats, you like your chances."
Holliday's fourth homer put the Cardinals up 2-0 after one inning for the second straight game, but they missed a shot to break it open in the third with the bases loaded when Pujols grounded into a forceout at the plate and Holliday fouled out to first.
NOTES: Marlins OF Logan Morrison, on the DL with a foot injury, may be close to a rehab assignment. Manager Edwin Rodriguez said Morrison is scheduled to take batting practice and perhaps shag some fly balls Wednesday. ... Cardinals manager Tony La Russa said SS Ryan Theriot, who led the majors with eight errors but was batting .306, has been a "significant plus" overall. ... The Cardinals have grounded into a major league-high 41 double plays. ... McClellan allowed four runs in five innings, his shortest outing in his first year in the rotation.
[Associated Press;
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