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While it's the 49ers defense that has been so dominant stopping the run -- now 31 straight games without allowing a 100-yard rusher -- the Giants had to think they had solved San Francisco by stopping Gore.
But Smith completed at least three passes to four different receivers, including tight end Delanie Walker's six receptions for 69 yards.
It was a day of defense. San Francisco had 77 total yards rushing to 93 for New York.
The first half featured seven possessions, five field goals and no punts.
Gore, the two-time Pro Bowler, already was nursing a tender right ankle that has bothered him on several occasions this season before hurting his knee Sunday and watching much of the second half in a red jacket on the sideline.
Gore has 7,196 yards rushing and needs 149 more to pass late Hall of Famer Joe Perry (7,344) for the most in franchise history.
Manning finished 26 for 40 for 311 yards and two TDs with two interceptions.
[Associated Press;
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