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Among the most highly anticipated of those drugs is the anti-clotting pill Eliquis, which is approved in the European Union for preventing clots in patients getting hip or knee replacement surgery. Bristol and its partner on the drug, Pfizer Inc., are seeking U.S. approval for the drug for stroke prevention, which would allow them to market it for millions more patients. The Food and Drug Administration has given Eliquis a priority review, with a March 28 target date for a ruling. Also scheduled to lose patent protection in the coming year is the blood pressure drug Avapro. Sales of that drug and its foreign counterpart Avalide fell 23 percent, to $195 million. That's because they have generic competition in Canada, a rival's similar drug has generic competition in many countries, and one of the three dosage forms isn't available due to a recall. Sales of the company's second biggest product, schizophrenia and bipolar drug Abilify, rose 4 percent to $737 million. For full-year 2011 the company earned $3.71 billion, or $2.16 per share, on sales of $21.24 billion. Excluding one-time items income was $2.28 per share.
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