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The Rams stuck with Amendola, who matched the first-half reception record set by the Colts' Reggie Wayne in 2007. Amendola finished with 15 catches, tying the franchise record, for 160 yards, helping the Rams exploit a defense that gave up 32 points in the opener.
St. Louis was 7 for 12 on third down conversions and totaled 452 yards. After his fourth career 300-yard passing game, Bradford, the first overall pick in 2010, said there wasn't extra incentive to match RG3.
"I go about it the same each week," Bradford said. "I need to play at a high level, play my best to give this team a chance to win, and I think I did that today."
The Redskins missed a good chance of forcing overtime when Josh Morgan was whistled for unsportsmanlike conduct for throwing the ball at Rams cornerback Cortland Finnegan. Coach Mike Shanahan opted for a 62-yard field goal attempt on fourth-and-16. Billy Cundiff's attempt was wide right and well short with 1:13 to play.
"I thought we were going for it," Griffin said. "But in a dome, 62 (yards) is far, but it's not that far. I was on a knee and I hoped that it would go through."
The Redskins lost defensive end Adam Carriker and outside linebacker Brian Orakpo to injuries early in the first quarter, while Rams offensive tackle Rodger Saffold was helped off with a right knee injury.
Orakpo and Saffold were hurt on the same play. Orakpo stripped Bradford and Saffold recovered the fumble and carried it 7 yards, but crumpled to the turf on the tackle.
NOTES: Amendola tied the franchise single-game record shared by Isaac Bruce and Flipper Anderson. ... Bradford passed for 300 or more yards for the fourth time in his career and threw for three TDs for the second time. ... Rams rookie punter Johnny Hekker averaged 54.3 yards on three attempts.
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