Tyson Gay, Asafa Powell and Sherone Simpson are among a number of athletes to fail recent tests ahead of the world championships next month.
Bolt says "it's going to set us back a bit," adding that he hopes to "help people forget what has happened" with his own performances and stressing: "I am clean."
The Jamaican said he has had one text-message exchange with compatriot Powell since the former 100-meter world record-holder tested positive for the stimulant oxilofrone.
Bolt told him "to stay strong."
Bolt was speaking in London where he competes on Friday for the first time since his three gold medals at the Olympics a year ago.
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