The result snapped the Orioles' four-game winning streak.
DeGrom (12-6), last season's National League Rookie of the Year,
gave up five hits with one walk and six strikeouts.
"I just try to go up there and put up zeros and let the rest take
care of itself," said deGrom, who lowered his ERA from 2.03 to 1.98.
DeGrom retired 11 straight batters before allowing a two-out double
to shortstop J.J. Hardy in the fifth.
"He one of the best in the game," Mets manager Terry Collins said
about deGrom. "I talk to other managers and he is one of the first
guys they ask about. He's very, very good."
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Granderson gave the Mets a 1-0 lead when he belted his
franchise-record seventh lead-off homer of the season over the right
field scoreboard.
New York increased their lead to 2-0 in the third on an RBI double
by Murphy.
Granderson provided a 3-0 lead with another solo shot in the fifth,
his third multi-homer game of the season.
An error by Orioles second baseman Jonathan Schoop on a potential
double-play helped the Mets score two crucial runs in the ninth.
"There were some mistakes I made today and I've got to be better,"
said Schoop. "I've got to be better for my teammates and better for
myself."
Schoop's miscue set up a sacrifice fly by third baseman Daniel
Murphy while Baltimore right-hander Brad Brach threw a wild pitch
that allowed shortstop Wilmer Flores to score.
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Mets closer Jeurys Familia entered and walked home two runs before
getting third baseman Manny Machado to ground out to end the game,
picking up his 33rd save.
Baltimore right-hander Kevin Gausman (2-5) had another effective
start with little run support.
He allowed three runs on six hits with a walk and six strikeouts
over six innings.
"Kevin gave us a good chance to win," Orioles manager Buck Showalter
said. "We knew there weren't going to be many opportunities with
deGrom out there.
"But Kevin held up pretty well, I thought. Held them in check,
finished strong like he's done his last two or three outings. It was
good to see him pitching competitively for us."
(Compiled by Greg Stutchbury)
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