Lacking awareness, people with the elevated blood sugar levels were
also less likely to make lifestyle changes such as getting more
exercise or eating less sugary food that might prevent them from
ultimately becoming diabetic.
“People with pre-diabetes who lose a modest amount of weight and
increase their physical activity are less likely to develop
diabetes,” lead study author Dr. Anjali Gopalan, a researcher at the
Philadelphia VA Medical Center, said by email. “Our study
importantly shows that individuals with pre-diabetes who were aware
of this diagnosis were more likely to engage in some of these
effective and recommended healthy lifestyle changes.”
Globally, about one in nine adults have diabetes, and the disease
will be the seventh leading cause of death by 2030, according to the
World Health Organization.
Most of these people have Type 2, or adult-onset, diabetes, which
happens when the body can't properly use or make enough of the
hormone insulin to convert blood sugar into energy.
Average blood sugar levels over the course of several months can be
estimated by measuring changes to the hemoglobin molecule in red
blood cells. The hemoglobin A1c test measures the percentage of
hemoglobin – the protein in red blood cells that carries oxygen –
that is coated with sugar, with readings of 6.5 percent or above
signaling diabetes.
But A1C levels between 5.7 percent and 6.4 percent are considered
elevated, though not yet diabetic.
More than one third of U.S. adults have such elevated blood sugar
levels and each year about 11 percent of them progress to having
full-blown diabetes, Gopalan and colleagues note in the American
Journal of Preventive Medicine.
To gauge awareness of this heightened diabetes risk among people
with the condition, researchers weeded out people who said they
already had the disease. Then, they reviewed A1c test results for
the rest.
Out of 2,694 adults with test results showing elevated A1c, only 288
people were aware of their status.
People who were aware of their condition were about 30 percent more
likely to exercise and get at least 150 minutes of moderate activity
each week.
They were also about 80 percent more likely to attempt weight loss
and to have shed at least 7 percent of their body weight in the past
year.
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In 2014, the U.S. Preventive Services Task Force, a
government-backed independent panel that reviews medical evidence,
said that screening for diabetes risk does help to identify people
headed for full-blown disease and can help some of them to avert it
with medication and lifestyle changes.
It’s possible that some patients in the current study had been told
about their status but didn’t recall or didn’t understand the
specific way researchers asked about the condition, said Dr. Laura
Rosella, a public health researcher at the University of Toronto.
“The health care provider has to tell the patient that they don’t
meet the criteria for diabetes but they aren’t quite out of the
woods, which can be a challenging concept to get across,” Rosella,
who wasn’t involved in the study, said by email. “This challenge
could explain the low awareness.”
Some patients may also have been tested for diabetes using another
measurement known as an oral glucose tolerance test, which can get
different results than screening for A1c, said Dr. Robert Cohen, a
diabetes specialist at the University of Cincinnati College of
Medicine.
“People can pass by one and miss by the other and it is confusion,”
Cohen, who wasn’t involved in the study, said by email. “Many
labeled as pre-diabetes by A1c would have diabetes if tested by the
gold standard oral glucose tolerance test.”
SOURCE: http://bit.ly/1JoxlgZ American Journal of Preventive
Medicine, online June 16, 2015.
[© 2015 Thomson Reuters. All rights
reserved.] Copyright 2015 Reuters. All rights reserved. This material may not be published,
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