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 Researchers found that testing for diabetes using blood that appears
on the gums during a routine oral cleaning might be just as accurate
as a standard screening that gets a blood sample by pricking the
finger with a tiny needle.
"There are more than 8 million people in this country who have
diabetes and don't know it, and many of these people see a dentist
much more regularly than they see a primary care provider," said
lead study author Sheila Strauss.
"If dentists can screen for diabetes, it may help people get treated
sooner when we can get better results managing their disease," said
Strauss, an associate professor of nursing and co-director of the
Statistics and Data Management Core for New York University's
colleges of nursing and dentistry.
Worldwide, nearly one in 10 adults had diabetes in 2014, and the
disease will be the seventh leading cause of death by 2030,
according to the World Health Organization.
Most of these people have type 2, once known as adult-onset,
diabetes, which is associated with obesity and aging and happens
when the body can't properly use or make enough of the hormone
insulin to convert blood sugar into energy.
Strauss and colleagues focused their research on testing hemoglobin
A1c, a protein in red blood cells that gets coated with sugar over
time, making it a gauge of average blood sugar levels for the past
two or three months.
The researchers collected blood samples taken from the gums and the
fingers of 408 people treated at dental clinics in New York City.
They tested for diabetes, when A1c is at least 6.5 percent, and for
elevated “prediabetic” A1c levels of at least 5.7 percent.
To make sure they got enough blood from the gums, they only included
people in the study who said that their gums bled when they brushed
or flossed their teeth.
The study team also limited participation to people at greatest risk
for diabetes. To be included, people had to be at least 45 years
old. Or, if they were younger, they had to be overweight and have at
least one other risk factor such as an immediate family member with
diabetes, a daily routine with little or no exercise, or an
ethnicity or race with high diabetes risk, including Latino, black,
Native American and Pacific Islander.
The oral-blood and finger-prick test results matched in 97.8 percent
of cases diagnosing diabetes, and in 92.9 percent of cases finding
prediabetes. And, the oral blood test was able to accurately rule
out diabetes 99.1 percent of the time, according to the results
published in the American Journal of Public Health.
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Because the sample for the study wasn't random, and participants
were instead selected based on their expected risk for diabetes,
it's possible that the results might not apply to a wider population
of people, Strauss said.
One advantage of the selection criteria, though, is that many people
with bleeding gums have periodontal disease or gingivitis – both
oral health problems that are more common among diabetics, she said.
While the screening approach tested in the study would need to be
proven effective by additional research, the possibility of dentists
doing oral screenings for diabetes has the potential to help many
undiagnosed people get treatment, said Betul Hatipoglu, an
endocrinologist and clinical associate professor of medicine at the
Cleveland Clinic in Ohio.
To be sure, dentists would need training on how to explain the test
results to patients who are positive for prediabetes or diabetes,
and they would also need a plan in place to refer these people to
specialists who can treat the disease, added Hatipoglu, who wasn't
involved in the study.
"If the test in this study proves effective with more research, it
is going to help get many individuals, especially young adults, who
are not going to see a primary care provider unless they are sick,"
Hatipoglu said.
"I can also see this helping men in their 30s who don't see anybody
except to get their teeth cleaned, or women who only go to the OB-gyn
to get an annual checkup or prenatal care and don't think about
anything else," she said.
SOURCE: http://bit.ly/1EmSzr4 American Journal of Public Health,
online February 25, 2015.
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