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			 Shares in Allergan jumped 11 percent in premarket trade to $320 by 
			1120 GMT on the reports. 
			 
			The healthcare sector has seen an unprecedented wave of deals since 
			early 2014, from large drugmakers buying up smaller rivals, to 
			consolidation among makers of generic medicines and tie-ups between 
			insurers. 
			 
			A bid for Allergan, which has a market value of $113 billion, would 
			be Pfizer's second recent attempt to acquire a big rival, following 
			its unsuccessful courtship last year of Anglo-Swedish 
			pharmaceuticals group AstraZeneca Plc. 
			 
			Combining Allergan and Pfizer, which is worth $219 billion, would 
			create the world's largest healthcare group with a market value of 
			around $330 billion, ahead of Johnson & Johnson on $278 billion. 
			 
			A Pfizer spokesman said it "does not comment on market rumor and 
			speculation". Allergan also declined to comment. 
			
			  
			The potential for lowering Pfizer's tax bill by switching its 
			headquarters from the United States to the United Kingdom was touted 
			by Chief Executive Officer Ian Read as a key reason for the proposed 
			AstraZeneca deal. 
			 
			A takeover of Allergan could offer similar advantages given that the 
			Botox-maker is based in lower-tax Dublin. A U.S. attempt to crack 
			down on such tax avoidance deals led to the collapse of AbbVie Inc's 
			bid to buy Shire Plc, but it is unclear whether those rule changes 
			would preclude potential tax advantages from a Pfizer-Allergan deal. 
			 
			"When you're the size of Pfizer, an acquisition like this may be the 
			only choice you have in order to be able to move the needle for 
			sequential growth...so the question now becomes, if not this, what, 
			and if not now, when?" said WBB Securities' analyst Stephen Brozak. 
			 
			Pfizer, the largest U.S. drugmaker, has also been suggested as a 
			possible acquirer of GlaxoSmithKline Plc and Shire, and shares in 
			these two companies fell 1.5 and 1.8 percent on Thursday morning in 
			London. 
			 
			REVENUE BOOST 
			 
			Allergan would give Pfizer, whose revenues are expected to slide 3.3 
			percent this year, a boost in top-line growth. The Botox-maker's 
			revenue is seen increasing 39 percent this year, according to 
			Thomson Reuters I/B/E/S estimates. 
			 
			Bernstein analyst Tim Anderson said Allergan was a good fit and 
			Pfizer might feel now was the right time to do a deal, given a 
			recent market correction that has made Allergan look cheap. 
			 
			
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			The merger talks are in early stages, and may not yield an 
			agreement, while other details are unclear, the Wall Street Journal 
			said. (http://on.wsj.com/1XA0qdo) 
			The Financial Times, which reported the talks later, described the 
			talks as preliminary. Reuters was not immediately able to confirm 
			the reports. 
			 
			Allergan became the third-largest generic drugmaker in the United 
			States after combining with Actavis in March. 
			Its chief executive, Brent Saunders, has been eager to do deals, 
			having first orchestrated the sale of Forest Laboratories Inc, where 
			he was initially CEO, to Actavis, then using the latter to seal the 
			$66 billion purchase of Allergan. 
			 
			Following the Actavis tie-up, Allergan sold its generic drugs 
			business to Israel's Teva Pharmaceutical Industries in July for 
			$40.5 billion in cash and stock. And Saunders said after that he 
			hoped to use those proceeds to do another large, "transformational" 
			merger. 
			 
			In its first full quarter after the Actavis deal, Allergan reported 
			second-quarter revenue of $5.76 billion, led by $632 million in 
			sales of wrinkle blocker Botox. Other top-selling drugs include dry 
			eye treatment Restasis and Alzheimer's drug Namenda. 
			 
			Pfizer recently reported third-quarter revenue of $12.1 billion, 
			including $1.58 billion for its Prevnar pneumococcal vaccines and 
			$947 million for pain drug Lyrica. 
			 
			While Pfizer wanted to buy AstraZeneca in part to boost Pfizer's 
			pipeline of cancer drugs, a deal with Allergan would involve 
			dermatology drugs and generics. 
			 
			(Additional reporting by Ben Hirschler and Deena Beasley; editing by 
			Lisa Shumaker, Greg Mahlich) 
			[© 2015 Thomson Reuters. All rights 
				reserved.] Copyright 2015 Reuters. All rights reserved. This material may not be published, 
			broadcast, rewritten or redistributed. 
			
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