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 When women don’t recognize this, they may suffer worse outcomes, a
fate that is even more likely in black and Hispanic women, according
to the AHA.
The organization published its first comprehensive statement on
gender differences in heart attack patients in its journal
Circulation.
“Women seem to do worse for several reasons,” said Dr. Laxmi Mehta,
the lead author of the recommendations and the director of women’s
cardiovascular health at Ohio State University in Columbus.
Importantly, people don’t realize that while both sexes may
experience chest pain before or during a heart attack, women may be
more likely to have unusual symptoms instead, such as shortness of
breath, nausea or vomiting, and back or neck pain.
Then, when they do get to a hospital, women may be less likely than
men to receive medications that help to prevent clots, decrease the
heart’s workload and lower blood pressure or cholesterol.
“There is a lot at stake for women when there is a delay in
treatment or lack of adherence to recommended therapies,” Mehta
added by email. “Women face higher rates of being readmitted to the
hospital, heart failure and death.”
Biology is also part of the problem.
Even though both women and men get heart attacks caused by blockages
in the main arteries leading to the heart, the way the clots develop
may differ, according to the scientific statement.
Men tend to have a more “classic” type of blockage where plaque
ruptures off the artery wall, forms a blood clot and causes a
complete halt of blood flow through the artery to the heart, said
Dr. Sheila Sahni, chief fellow in cardiovascular disease at the
David Geffen School of Medicine at the University of California Los
Angeles.
“Women, more often, tend to have a plaque erosion where smaller
pieces of plaque break off, become exposed and cause the formation
of smaller blood clots which may or may not cause total occlusions
all at once, leading to a more subtle presentation,” Sahni, who
wasn’t involved in the study, said by email.
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In addition, women tend to be about a decade older than men when
they suffer heart attacks, potentially making them frailer and more
likely to suffer from other health problems such as diabetes that
can make their treatment more complicated, Sahni added.
Risk factors also differ by gender, with high blood pressure more
strongly associated with heart attacks in women than in men. For
young women with diabetes, the risk for heart disease is four to
five times higher than it would be for a similar young man.
Race, too, is an issue. Compared to white women, black women have a
higher incidence of heart attacks in all age categories and young
black women have greater odds of dying before they leave the
hospital. Black and Hispanic women are also more likely to have
heart-related risk factors such as diabetes, obesity and high blood
pressure at the time of their heart attack.
Once a heart attack begins, the best way for women to minimize
damage is to get help quickly, said Dr. Leslie Cho, director of the
women’s cardiovascular center at the Cleveland Clinic in Ohio.
“Time is muscle,” Cho, who wasn’t involved in the study, said by
email. “If women are diagnosed and treated later in the course of
the heart attack, they can suffer from irreversible heart damage.”
SOURCE: http://bit.ly/1RJs3jS Circulation, online January 25, 2016.
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