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			 Newly-learned information turns into long-term knowledge through a 
			process of stabilization and integration of memories, the study team 
			writes in Current Biology. This requires certain brain chemicals 
			that are also released during physical exercise, including dopamine, 
			noradrenaline (norepinephrine) and a growth factor called BDNF, they 
			explain. 
 “The brain processes new memories for a while after learning. 
			Physical exercise is able to improve these post-learning processes,” 
			senior author Guillen Fernandez, director of the Donders Institute 
			for Brain, Cognition, and Behavior in Nijmegen, the Netherlands, 
			told Reuters Health by email.
 
 To explore when exercise would most improve learning, researchers 
			recruited 72 participants and tasked them with learning to match a 
			series of 90 locations with pictures over a 40-minute period.
 
 The participants were split into three groups: one group exercised 
			immediately after learning, one group exercised four hours later and 
			one group did not exercise at all.
 
			
			 
			The exercise groups did interval training for 35 minutes on a 
			stationary bike, including spurts at maximum intensity.
 Two days later, the participants returned to the lab to test how 
			much of what they’d memorized they could recall. During the recall 
			test, the each subject was in a MRI scanner so researchers could 
			monitor activity in different areas of the brain.
 
 The group that had exercised four hours after learning remembered 
			significantly more information on the follow-up test, while the 
			immediate-exercise group did no better than the group that did not 
			exercise.
 
 Activity in the hippocampus, a part of the brain associated with 
			forming memories, was very similar among people in the 
			delayed-exercise group during the recall task, but less consistent 
			in the other participants, the researchers note.
 
 They speculate that the consistency of activation in the hippocampus 
			in the delayed-exercise group could indicate greater “efficiency or 
			coherence” in the way the brain pulls up the memory and “might 
			relate to differences in memory strength.”
 
 While strong memories will be remembered no matter what, Fernandez 
			said, weaker memories that would normally be forgotten within a day 
			may last longer if the brain releases more dopamine and 
			norepinephrine.
 
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			People looking to improve their learning should perform fairly 
			intense exercise to make sure that enough of the critical brain 
			chemicals are released, he said, but cautioned against taking this 
			too far. “Very intensive exercise might also have negative effects.”
 The authors note that more research is needed to determine if 
			exercise will help memories last beyond the two-day period they 
			studied.
 
 They add that the type of memory may be important, and that 
			procedural or “body” memory of activities like tying a shoe may be 
			better helped by immediate exercise than other kinds of memories.
 
 Having a regular exercise routine may be helpful as well said Marc 
			Roig, an assistant professor at McGill University in Montreal who 
			studies the effect of cardiovascular exercise on memory.
 
 Several weeks of cardio exercise, such as jogging, can make the 
			hippocampus larger and improve people’s memory, he told Reuters 
			Health.
 
 The type of exercise may not be important, though, added Roig, who 
			was not involved in the new study. “Most studies have looked into 
			aerobic exercise but recent data shows that resistance training and 
			high intensity interval training may also be beneficial.”
 
 “When thinking about how to maximize your training regimen to 
			improve/maintain memory do not ask yourself only what type of 
			exercise, intensity or frequency is the best. Ask yourself when to 
			train to achieve the best results,” Roig said.
 
 SOURCE: bit.ly/1OsVDu4 Current Biology, June 16, 2016.
 
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