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			 The loss on the Miami hardcourts was the first since 2012 for 
			William, who had swept the last three titles in her unofficial home 
			tournament. 
 "I'm really thrilled," said Kuznetsova after registering her first 
			win over Williams since 2009. "I'm sorry fans, who are disappointed 
			that Serena's not going to keep playing, but for sure she'll be at 
			more events than here.
 
 "I'm really happy with my performance. I tried to stay at a good 
			level the whole game. I think I did that pretty well and I'm happy 
			with the way I served today."
 
 It was a day of dramatic upsets at Crandon Park, as Williams stepped 
			onto the Stadium court for her Round of 16 match immediately after 
			third-seeded world number two Agnieszka Radwanska of Poland was 
			tripped up by 19th-seeded Swiss Timea Bacsinszky 2-6 6-4 6-2.
 
			
			 Radwanska was the winner on the Miami hardcourts in 2012 before 
			Serena Williams embarked on her three title run.
 The upsets continued into the afternoon with fourth-seeded Spaniard 
			Garbine Muguruza falling 7-6(6) 7-6(4) to 13th-seeded Belarusian 
			Victoria Azarenka, still in top form following her victory this 
			month at Indian Wells.
 
 Second-seeded Angelique Kerber narrowly avoided being another victim 
			as she survived Timea Babos 6-2 3-6 6-4 in the day's late match.
 
 A tight first set saw both Williams and Kuznetsova register a break 
			but neither player could gain the upper hand, sending the opener to 
			a tie-break which the top-seeded American dominated 7-3 with the 
			help of a pair of thundering aces.
 
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			A battling Kuznetsova controlled the second set from the start, 
			breaking the 21-times grand slam winner to go up 3-1 then sweeping 
			the next three games to level the contest at a set apiece.
 The Russian upped the pressure with a pair of breaks to start the 
			third as she stormed through the opening three games before Williams 
			finally stopped the bleeding with a break of her own at 3-1.
 
 The relief was brief, however, as former U.S. and French Open 
			champion Kuznetsova immediately hit back with yet another break and 
			went on to finish off the upset in just over two hours.
 
 In other action, fifth-seeded Romanian Simona Halep eased into the 
			quarters with a tidy 6-3 6-4 decision over British wildcard Heather 
			Watson.
 
 Britain, however, will be represented in the last eight as Johanna 
			Konta tamed another Romanian, Monica Niculescu, 6-2 6-2.
 
 (Reporting by Steve Keating in Toronto; Editing by Larry 
			Fine/Sudipto Ganguly)
 
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