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 One billion people, mainly in Asia, Africa and Latin America, are
still treated each year for at least one of 18 neglected tropical
diseases known as NTDs, it said.
Dengue, onchocerciasis (river blindness), and sleeping sickness are
among those carried by mosquitoes or flies that are spreading from
rural areas to urban slums, the WHO warned.
"There is no group of diseases that is so intimately linked to
poverty," Dr. Dirk Engels, director of WHO's department of control
of neglected tropic diseases, told a news briefing.
"A number of companies have accompanied us in the scaling up by
making more medicines available. Is that enough? No, there are still
diseases that are neglected and we still have problems with access
to basic medicines," he said.
GlaxoSmithKline, Novartis and Sanofi are among major donors, WHO
says. Merck said earlier it was developing a children's formula of
its drug to treat schistosomiasis, a parasitic worm disease which
kills 280,000 a year in Africa.
New products need an access plan for patients "because just counting
on the commercial mechanisms won’t work", Enders said.
The Bill and Melinda Gates Foundation is backing research and
development into NTDs. Bill Gates met with CEOs of major
pharmaceutical companies in Geneva on Tuesday.
"Good progress, some of these diseases are on track to be done
(eliminated) by 2020, some by 2025. Some will take longer than
that," Gates told a news conference, noting that there were only
3,000 cases of sleeping sickness last year.
EXPENSIVE MEDICINES
Needs remain huge despite the fight over the past decade and a 2012
London meeting to galvanize attention and set targets, WHO said.
"Cutaneous leishmaniasis, for instance. It doesn’t kill so it
attracts less attention, but it is really disfiguring and it causes
a lot of stigma and a lot of mental problems," Engels said of the
disease spread by female sandflies.
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"The medicines exist...They are too expensive and (neither) people
nor countries have the ability to pay."
Drugs companies currently have 109 research and development projects
for medicines or vaccines for NTDs, which typically take 10-15 years
to develop, the International Federation of Pharmaceutical
Manufacturers & Associations (IFPMA) said.
"There are quite a number of new medicines and diagnostics in the
pipeline, which may actually further change the perspective for
these neglected tropical diseases and hopefully allow us to go
further towards eliminating or near eliminating these diseases by
2030," Enders said.
Only 25 human cases of Guinea worm disease were reported last year,
"putting eradication within reach", he added.
"We have just acknowledged the first African country that has
eliminated lymphatic filariasis as a public health problem – Togo –
so that may be a start of a number of them," Enders said.
The mosquito-borne infection, also known as elephantiasis, causes
enlargement of limbs and genitals from adult worms in the lymphatic
system.
(Editing by Gareth Jones)
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