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			 The Swiss drugmaker also dismissed speculation it was looking to 
			unload its diabetes care unit, saying it was "committed" to the 
			business. 
 Core earnings per share this year are now forecast to grow broadly 
			in line with a low- to mid-single-digit sales rise, the company 
			said.
 
 That contrasts with 2016 when core earnings per share rose 5 percent 
			to 14.53 Swiss francs ($14.66), while sales grew 4 percent in 
			constant currencies to 50.6 billion francs.
 
 The drugmaker's three cancer blockbusters Rituxan, Herceptin and 
			Avastin, which account for annual sales of more than 20 billion 
			Swiss francs, face impending competition from so-called biosimilar 
			copies.
 
 The first copies of Rituxan and Herceptin could arrive in Europe 
			later this year.
 
 Consequently, Chief Executive Officer Severin Schwan said he has 
			dialed back 2017 profit growth expectations on the grounds that he 
			must invest in new products including cancer immunotherapy Tecentriq, 
			Cotellic for skin cancer and lung cancer drug Alecensa to fill the 
			void.
 
 "We're going through a transition of our portfolio but the good news 
			is, we can overcompensate with the launch of new medicines," Schwan 
			said on a conference call.
 
			
			 
			Roche shares were up less than 1 percent at 0840 GMT (03:40 a.m. 
			ET).
 Analysts noted this was the first time in three years that Schwan, 
			an Austrian who has led Roche since 2008, has not made a more 
			bullish prediction for margin expansion.
 
 "Biosimilars will hit Roche in the current year in Europe and then 
			in 2018 in America in a big way, putting Roche under pressure to 
			keep up new pipeline news and successful drug launches," Michael 
			Nawrath, a Zuercher Kantonalbank analyst, wrote in a note to 
			investors.
 
 Schwan played down the threat posed by U.S. President Donald Trump's 
			call for drugmakers to cut prices and invest more in the United 
			States, arguing that innovative companies would still be rewarded 
			and pointing out Roche's big U.S. presence via its Genentech unit.
 
 Core net income in 2016 rose to 12.7 billion francs, Roche said, 
			compared with the 12.8 billion franc average estimate by analysts in 
			a Reuters poll.
 
			
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			Roche proposed raising its dividend to 8.20 francs per share, below 
			the 8.45 franc average estimate in the poll.
 Sales of Tecentriq, Cotellic and Alecensa added 400 million Swiss 
			francs to sales, and Schwan expects that figure to grow 
			significantly.
 
			DIABETES COMMITMENT
 He anticipates Ocrevus, Roche's new multiple sclerosis medicine, to 
			be approved by the U.S. Food and Drug Administration in March after 
			it was delayed from December. First sales are set for April.
 
 Overall, Roche reported that sales in its main drugs business rose 3 
			percent to 39.1 billion francs, while diagnostics sales added 7 
			percent to 11.5 billion francs.
 
 Roche's diabetes care business, part of the diagnostics unit, 
			continued to face price pressure, especially in the United States. 
			Still, Schwan remains committed to the business.
 
 "We are well positioned in this segment, where we are the market 
			leader," Schwan said. "It's a difficult situation we are going 
			through but we remain committed to this business."
 
 ($1 = 0.9903 Swiss francs)
 
 (Additional reporting by Ben Hirschler; Editing by Michael Shields 
			and Louise Heavens)
 
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