SC Cardiologists
participate in Chronic Heart Failure Treatment Study
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[May 30, 2018]
Springfield Clinic cardiologists are
approved to enroll patients in a global study to test a new therapy for
chronic heart failure. The drug, MK-1242 (vericiguat), will be tested
against a placebo to see if it’s a safe, viable addition to normal
treatment for decreasing heart failure-related hospital visits and
increasing longevity.
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Chronic heart failure is an incurable condition where the heart
muscle can’t pump properly due to weakness or damage. Damage to the
heart can be caused by a single event, like a heart attack, or
long-term conditions like high blood pressure, diabetes or heart
disease; once the heart is damaged, it can’t heal. According to the
study protocol, heart failure is a leading cause of disease and
death due to cardiovascular issues and “constitutes a major public
health problem worldwide.” In the US, an estimated 5.1 million
people have heart failure.
Adeeb Ahmed, MD, FACC, FSCAI, FACP, Yasmin Hamirani, MD, and
principal investigator Ish Singla, MD, are the participating
physicians at Springfield Clinic. Merck, the study sponsor,
approached the Clinical Research team and the doctors to bring
Springfield Clinic on as a study site and begin recruiting central
Illinois patients for this global study, which will include nearly
5,000 patients worldwide. Drs. Ahmed, Hamirani and Singla have all
participated in numerous research studies before, and this will be
the first collaboration for them in the Springfield Clinic
Cardiology Department.
Eligible patients can still join the study if they are interested in
participating. Patients who have been hospitalized with heart
failure symptoms in the last six months or have required IV
diuretics for an acute outpatient heart failure episode within the
last three months may be considered for the study. Patients will be
followed until the required number of cardiovascular events have
occurred, approximately 10–18 months.
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Patients interested in being screened for participation can call Springfield
Clinical Research at 217.528.7541 ext. 14664. Patients who participate in the
study receive study-related visits and medication free of charge, along with a
stipend to cover the cost of travel or other expenses.
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About Springfield Clinic
Springfield Clinic is a progressive, physician-led multispecialty medical group
devoted to providing the highest quality health care to its patients. More than
400 physicians and advanced practitioners deliver value-based care in
approximately 80 medical specialties and sub- specialties. As one of the largest
private multispecialty medical clinics in Illinois, Springfield
Clinic currently employs over 2,000 clinical and administrative staff members
who are committed to leadership in quality, service and technology. For more
information, go to www.Springfield
Clinic.com.
[Rachel Gasperin
Springfield Clinic Marketing & Communications Dept.] |